Amphipterygium adstringens is a plant widely used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Amphipterygium adstringens is a deciduous shrub or small tree, commonly growing about 3 – 6 metres tall, with a broad and rather flat or sometimes narrow . PDF | Extracts from the bark of Amphipterygium adstringens, known as Cuachalalate, is in Mexico commonly used to treat several gastrointestinal disorders.

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The experiment was performed by duplicate in three independent tests. The cell line has less than 20 passages as laboratory good practices. The increasing cancer incidence is closely related to the raise in life expectancy and longevity that consequently results in a longer exposure to carcinogenic agents such as pollution, UV radiation, and microorganisms [ 44 ].

Published online Aug According to literature, phenols are the main responsible compounds of the antioxidant activity [ 24 ]; for this reason, the AaEE has been analyzed. Natural products, herbs, and dietary components have shown therapeutic effect against inflammatory colitis [ 37 ].

Amphipterygium adstringens – Wikipedia

Antimicrobial activity of northwestern mexican plants against Helicobacter pylori. These are significant activities at low concentrations considering that CE is a mixture of nonpurified compounds, such as those found in actual traditional use of A.

It has been proposed that an imbalance between amphipteryfium and antioxidant mechanisms may play an important role in the development of intestinal inflammation and mucosal tissue injury in colitis [ 27 ]. Microorganisms in Industry and Environment: Plant-based, traditional remedies are now being used as alternative therapeutic strategies.


Body weight loss and bloody amphiptwrygium were observed in mice acutely exposed to DSS. The male flower is actinomorphic. Ameliorative effects of 3,4-oxo-isopropylidene-shikimic acid on experimental colitis and their mechanisms in rats. Crude extract CE of A. There exists an increasing prevalence of infections worldwide, due to, among other reasons, the growing resistance of pathogens to antibiotics and antifungals as well as alterations in the autoimmune system. Additionally, the constantly observed correlation between oral addtringens especially biofilm builders [ 28 ] with chronic inflammatory disease and cancer triggers the need for further research that contributes with novel sources of bioactive compounds.

Amphipterygium adstringens bark was obtained by Dr. Adstriingens, antimicrobial and cytotoxic activities of selected medicinal plants from Yemen. It is demonstrated here for the first time that oral administration of AaEE effectively attenuates colonic inflammation in mice.

This page was last edited on 18 Julyat Amphipterygium adstringens is a plant amphlpterygium used in Mexican traditional medicine for its known anti-inflammatory and antiulcer properties. Calculations were performed using GraphPad Prism version 6.

Amphipterygium adstringens

These effective antimicrobial and antiproliferative activities make A. Preparations and formulations of this CE can be improved and applied for daily use in dental products to prevent caries and periodontal diseases and concomitantly weaken the risk of cancer. The sections were also stained with Alcian blue to evaluate the presence of goblet cells.

The Folin-Ciocalteu method [ 22 ] was used to determine the total phenolic content of a 0. Although all of them have shown some grade of efficacy in these intestinal conditions, the frequency and severity of adverse effects, inconvenient dosing regimen, and partially prohibitive price limit their long-term use [ 34 ].


Doxorubicin was used as positive control. The weight loss, stool formation, and bloody stool scores were averaged to determine the DAI. Evidence-Based Complementary and Alternative Medicine.

After removing the solvent, 0. Therefore, our findings indicate that AaEE treatment of colitis might be reducing the extent of colonic injury by its antioxidant ability. View at Google Scholar A. Effect of plants used in Mexican traditional medicine on Candida albicans biofilm. Total Flavonoid Content Adstrinens Dowd method [ 23 ] was used to determine the flavonoid content.

De La Rosa, and G. The model used in this work to evaluate the antiproliferative activity was the assay with Sulforhodamine B an anionic dye that allowed the evaluation of antitumor activity through exposure of selected human tumor cell lines during exponential growth phase, at different concentrations of the A.

Mauricio Gonzalez, following the last revision of the genus Amphipterygium Julianaceae [ 46 ]. Antioxidant activity, total phenolic and flavonoid content of Morinda citrifolia fruit extracts from various extraction processes.

At least 3 sections from each colon were analyzed to produce each score value.